Fold&Dock
A rapid modeling tool for antibody-antigen and nanobody-antigen complexes
Antibody Sequence
Note:
Use ':' to separate the heavy and light chains. The heavy chain should come first!
Note:
You can only model one antibody sequence for a single antigen. All remaining entries in the fasta file will be ignored.
Input type:
Fasta file
Sequence (string)
Upload File:
Fasta sequence:
Antigen Structure
Note:
If you need only some of the antigen chains for docking, specify them without spaces ('ABC' for example).
Note:
We currently support antigens with sequence length of up to 600 amino acids.
Do docking
Antigen chains
Upload PDB File:
Number of PDB models
Additional options:
Visualize
Reconstruct side chains using modeller
Modeller license key
Enter your email address
Link to source code:
Available at GitHub
If you use Fold&Dock please cite:
T Cohen, D Schneidman-Duhovny.
End-to-end accurate and high-throughput modeling of antibody-antigen complexes
Contact:
tomer.cohen13 {at} mail.huji.ac.il
Acknowledgement:
We are grateful for the support of the Center for Interdisciplinary Data Science Research (CIDR) at the Hebrew University of Jerusalem. In particular, we would like to thank Haimasree Bhattacharya from CIDR for her contributions.
